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IMPORTANT MESSAGE REGARDING COVID-19: During this time of great uncertainty, we want to assure you that Diem is taking all necessary measures to protect you, our employees, and our community. As a Michigan-based company, we are now governed by state and federal directives designed to protect the health and safety of us all. At Diem, our on-site staff has been limited and those remaining are outfitted with personal protective equipment. We have instituted strict sanitation protocols, and we are closely monitoring individual wellness to protect you and the entire Diem family.

US DOMESTIC CUSTOMERS: To help offset possible Postal delivery delays, we now offer UPS Ground service as an option for shipping during checkout. This service is available for customers within the contiguous United States. Please be aware that this option does require payment of actual shipping charges at the time of purchase. Charges will vary depending on the destination and weight of the package.

Questions? Click here to email or contact customer service Monday-Friday at 888-876-5765.

Can Histamine Cause Itchy Skin?

Histamine and Itchy Skin

We’ve all had that itch that we just can’t scratch. And no, scratching it harder doesn’t make it any better (we’ve tried).

The key to beating an itch is to understand the cause of it. And whether it be an allergic reaction or DAO deficiency, itches can be caused by histamine.

When Histamine Causes Problems

When your body comes into contact with something that it recognizes as an allergy (like poison ivy or a medication), histamine is released from your mast cells to deal with it.

Histamine is also found in foods and can build up in the body in situations where you have a histamine intolerance/DAO deficiency and cannot break it down properly.

Histamine binds to protein receptors on nerve cells and the top layer of skin, which eventually causes itch signals to be sent to the brain via the spinal cord. And soon enough, you’re scratching.

How to Find Relief

First off, stop scratching! It really does make things worse. While the pain scratching causes temporarily covers-up the itchy feeling, your brain then releases serotonin to deal with the pain, which leads to more itchy signals being sent. The more you scratch, the worse it gets.

In cases where an allergy is causing the scratch, antihistamines can do the trick, preventing histamine from binding to receptors. Avoiding histamine-rich food can also reduce the amount of the chemical in your body. Taking an Umbrellux DAO capsule about 15 minutes before a meal can provide you with the diamine oxidase to break down histamine and stop symptoms of histamine intolerance.