Food Allergy vs Histamine Intolerance

Difference between Food Allergy and Histamine Intolerance

While the symptoms of Histamine Intolerance (HIT) may mimic allergic reactions, histamine intolerance is not a classical food allergy.

Rather, research suggests that histamine intolerance is mediated by a deficiency in levels and/or activity of the Diamine Oxidase enzyme.


Histamine Intolerance Chart

Symptoms of Histamine Intolerance

  • Vasodilation (flushing/reddening)
  • Hypotension/Tachycardia
  • Stuffy, Runny Nose/Sneezing
  • Swelling or red, watery eyes
  • Headache or Migraine
  • Diarrhea, cramps, bloating
  • Feelings of anxiety
  • Urticaria (hives)

Prevalence Statistics

Food Allergy and Food Intolerance Statistics